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SUPPLEMENT INGREDIENTS, CLINICAL STUDIES & VALIDATION

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GMP CERTIFIED LAB

All of our supplements use only the finest ingredients, undergo rigorous quality testing, and are scientifically formulated in a GMP certified facility.

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CLINICALLY STUDIED INGREDIENTS

 Many of the ingredients used in our supplements have been clinically tested and the reports are posted on NIH Pubmed.gov or similar sites.

NEURO86 SAFE BRAIN BOOST INGREDIENTS AND CLINICAL VALIDATION

ST. JOHN'S WART

 A Scientific Studies report (35700, 2016) states that St. John’s Wart “affects multiple neurotransmitters in a non-competitive synergistic manner, and may have nootropic potential.”  The meta-analysis incorporated studies that examined the effect of St. John’s Wart versus placebo on memory indices of task performance. "Thirteen independent studies (published 2000–2014) involving 20 experimental comparisons met our inclusion criteria. The results showed a large positive effect of [St. John’s Wart] on cognitive performance.” A similar study states that “The herb significantly (p<0.01) improved hippocampus-dependent spatial working memory in comparison with control and alleviated some other negative effects of stress on cognitive functions.”


St. John's Wort may also aid in enhancing metabolism and internal clocks to battle sleeplessness, irritability and chronic fatigue, and in removing chronic stress hormones from the body, boosting health and cognitive function. This herb may also be beneficial for women's health, since it helps reduce sensitivity of premenstrual symptoms, improves conditions of women having premenstrual and menopausal mood swings and helps alleviate pregnancy-related hemorrhoids or other stretched out areas of the body.


St. John's Wort may regulate hormonal activity as its active ingredients have strong effects on hormone regulation. The herb may lessen hypothyroidism symptoms and may aid the thyroid gland in producing adequate amounts of hormones. St. John's Wort's soothing nature and rich concentration of antioxidant and anti-inflammatory compounds may ease joint discomfort and muscle aches, and may help reduce inflammation of the cardiovascular system, helping lower blood pressure levels and stress levels on the heart.

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PHOSPHATIDYLSERINE

 Phosphatidylserine naturally functions within our bodies for the maintenance and health of the cell membranes, particularly our neuronal membranes. PS is known to provide a crucial benefit of bolstering cognitive health through maintenance of proper neurotransmitter levels as well as enhancing membrane mediated signaling of neurons. With age-associated cognitive decline becoming an increasing concern, it is important to maintain healthy levels of phosphatidylserine to reinforce proper neurological functions. Supplementation of phosphatidylserine may reduce the risk cognitive dysfunction in the elderly.


A large amount of in vitro studies utilizing primary human neurons have shown that phosphatidylserine may be vital for proper neuronal function. PS is known to be important in vesicular release of neurotransmitters from presynaptic terminals, transduction of neuron-to neuron signaling, preserving Na+/K+ balance, and regulate neuronal growth homeostasis. These essential neuronal functions eventually decline with age, and their proper maintenance is required in order to maintain proper neurological health and cognition. Several pre-clinical and clinical studies have shown that dietary supplementation of phosphatidylserine has both a neuroprotective and a neuro-enhancing effect: Aged preclinical models were fed various forms of phosphatidylserine. The researchers observed a significant improvement in three different, independent cognitive tests. Ultimately the authors of the study conclude that there was an increase in psychomotor capacity and overall cognitive improvement. A study was conducted wherein scientists took brain sections and incubated them with phosphatidylserine. The sheer act of exposing the brain to more phosphatidylserine led to an increase activity of neurons.


 A 2015 study posted on Pubmed.gov (NIH) states that PS "supports human cognitive functions, including the formation of short-term memory, the consolidation of long-term memory, the ability to create new memories, the ability to retrieve memories, the ability to learn and recall information, the ability to focus attention and concentrate, the ability to reason and solve problems, language skills, and the ability to communicate. It also supports locomotor functions, especially rapid reactions and reflexes." 

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GINKGO BILOBA

 The therapeutic properties of the ginkgo plant are said to include treatment for blood disorders and memory problems, enhancement of cardiovascular function and to improve eye health. Gingko contains high levels of flavonoids and terpenoids, antioxidants that may provide protection against oxidative cell damage from harmful free radicals. An Examine.com study says "There appears to be a fairly reliable increase in short term memory and free recall associated with ginkgo supplementation."


Also known as the maidenhair tree, ginkgo is one of the oldest species of tree in the world. The trees can grow more than 130 feet tall and can live for over 1,000 years. Some trees in China are said to be over 2,500 years old. The tree is considered to be a "living fossil" as it has continued to survive after major extinction events. Ginkgo biloba may offer a range of health benefits, including improving cognitive function. 


According to the University of Maryland Medical Center (UMM), "Gingko is widely used in Europe for treating dementia. Doctors started to use it because they thought it improved blood flow to the brain.

The benefits may include improved thinking and memory, better social behavior, and better ability to perform everyday tasks.


Ginkgo may also help alleviate the symptoms of anxiety. A study published in the Journal of Psychiatric Research found that people with generalized anxiety disorder who took ginkgo experienced better anxiety relief than those who took a placebo.

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BACOPA MONNIERI

Bacopa monnieri has been used for centuries in Ayurveda traditional medicine and has long been thought of as a “wonder herb.” Bacopa contains contains anthraquinones, phytosterol, and terpenoids, as well as numerous biologically active compounds, such as alkaloids (brahmine and herpestine), bacopasaponins, flavonoids (glucuronyl-7-apigenin, glucuronyl-7-luteolin, luteolin-7-glucoside, and luteolin), and saponins (bacogenins, bacosides, and bacopasides). These powerful compounds are responsible for the herb’s many pharmacological and therapeutic benefits. Bacopa is commonly known as a nootropic as It has been shown to help repair neurons that have become damaged, improve brain function, improve neuron communication, and protect brain cells from harmful chemicals that are responsible for neurological diseases linked to cognition and memory. Bacopa has also shown the ability to help regulate the body's response to both acute and chronic stress and may act as a potent adaptogen.


Bacopa may increase the effects of key neurotransmitters, such as serotonin, acetylcholine, noradrenaline, and dopamine, which can help bolster a sense of calm and maintain mood equilibrium. An imbalance of these key neurotransmitters is believed to play a significant role in maintaining mental health. Bacopa may be a natural anti-depressant and mood booster that lacks the side effects of some pharmaceutical drugs.


In research, bacopa has shown significant results with respect to anxiety and depression. This research showed that Bacopa did not produce any significant motor deficit, which suggests that it is unlikely to cause sedation. In another study, participants over the age of 65 who used bacopa demonstrated a decrease in both anxiety and depression.


 A 2017 study posted on Pubmed.gov (NIH) documents results that "support the beneficial mnemonic effect of Bacopa Monnieri, and suggest that this effect might be because of the increase of learning-associated synaptic machinery, resulting in the long-term potentiation enhancement and strengthening of hippocampal synapses, which plays a critical role in learning and memory formation."  

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HUPERZINE A

 Huperzine A is an herbal substance that comes from a plant called Chinese club moss (Huperzia serrata). In traditional Chinese medicine, it has been used for centuries to reduce inflammation and sharpen memory. Huperzine A may act as a cholinesterase inhibitor, which can prevent the breakdown of acetylcholine--a brain chemical essential to learning and memory. 


Huperzine A is also believed to enhance learning and memory and protect against age-related cognitive decline. It may also boost energy and increase mental alertness.  Several studies posted on Pubmed.gov (NIH) point to neuroprotective, cognitive function, and memory enhancement benefits. 

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N-ACETYL L-CARNITINE HCI

N-Acetyl L-Carnitine HCI (ALCAR) is known as an anti-aging nootropic that may improve brain functions as the acetyl group passes the blood-brain barrier and may improve mood, learning, and memory. It may also shuttle fuel (in the form of fatty acids) to muscle mitochondria to boost energy production and endurance while burning fat. A study posted on Pubmed.gov (NIH) says “These results indicate that ALCAR increases synaptic neurotransmission in the brain and consequently improves learning capacity.”

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NEURO86 EXTROVERTED LEADER FORMULA

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VITAMIN B-12

VITAMIN B-12 has been shown to keep the body’s nerve and blood cells healthy. A deficiency can cause fatigue, loss of appetite, and anemia and proper suppmentation may improve energy levels.

ASHWAGANDHA ROOT

ASHWAGANDHA ROOT: A study on Pubmed.gov (NIH) says "Ashwagandha may be effective in enhancing both immediate and general memory in people with MCI (mild cognitive impairment), as well as improving executive function, attention, and information processing speed." 

L-TYROSINE

L-TYROSINE is a precursor to dopamine, which may support sleep, learning, memory, and focus. A study on Pubmed.gov (NIH) says "...cognitive studies employing neuropsychological measures found that tyrosine loading acutely counteracts decrements in working memory and information processing that are induced by demanding situational conditions." 

SCHISANDRA

SCHISANDRA is believed to have a positive impact on the heart, lungs, and kidneys, and may have adaptogenic properties to help the body resist the effects of anxiety and stress. 

SELENIUM

SELENIUM may play a major role in supporting metabolism and thyroid function. Antioxidants may help reduce oxidative stress by keeping free radical numbers in check while lowering the risk of mental decline and thyroid problems. 

NEURO86 INTROVERTED LEADER FORMULA

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PHOSPHATIDYLCHOLINE

PHOSPHATIDYLCHOLINE can improve communication between nerves by increasing choline and acetylcholine levels in the brain. Studies show that introverts rely more on the acetylcholine neurotransmitter, which may improve the ability to think deeply, reflect, and focus. Studies on Pubmed.gov (NIH) say "phosphatidylcholine is a precursor of choline for acetylcholine synthesis" and "can be used as a safe and effective supplement for improving the neurological health of normal individuals and that they might also be beneficial in preventing cognitive and motor disorders later in life." 

VITAMIN-E OIL

VITAMIN-E OIL is a nutrient that's important for vision, reproduction, and healthy skin, blood, and brain functions. It has antioxidant properties that may protect cells against free radicals. 

NEURO86 INSTINCTUAL TRIAD FORMULA

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CHROMIUM PICOLINATE

CHROMIUM PICOLINATE may help lower cholesterol levels and benefit heart health. A study on Pubmed.gov (NIH) says "supplementation significantly attenuated body weight gain and visceral fat accumulation compared with the placebo group." 

GAMMA LINOLENIC ACID (GLA)

GAMMA LINOLENIC ACID (GLA) may activate metabolism and boost fat burning and energy. A study on Pubmed.gov (NIH) says "dietary gamma-linolenic acid oil reduces body fat content and facilitates fatty acid beta-oxidation in the liver."

CONJUGATED LINOLEIC ACID (CLA)

CONJUGATED LINOLEIC ACID (CLA) may help with fat loss, weight loss, and lean muscle mass retention.

VITAMIN B-5

VITAMIN B-5 (pantothenic acid and pantothenate) is vital to a healthy lifestyle and can help convert food into energy.

INOSITOL

INOSITOL (vitamin B8) may have various benefits such as aiding with mental health, including depression and metabolism. 

L-PHENYLALANINE (LPA)

L-PHENYLALANINE (LPA) can be converted to L-Tyrosine and L-dopa, norepinephrine, and epinephrine, which are vital for the body’s “fight or flight” stress response.

NEURO86 EMOTIONAL TRIAD FORMULA

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HORNY GOAT WEED

HORNY GOAT WEED may have positive effects on libido, emotional, and sexual brain centers and enhance several emotional brain functions. Studies show it may prevent cognitive decline and the breakdown of acetylcholine, a neurotransmitter involved in memory, focus, and learning. 

MACA ROOT POWDER

MACA ROOT POWDER is a nootropic that may support learning and memory. Clinical studies show libido increase, anxiety reduction, and mood enhancement. A study on Pubmed.gov (NIH) says "In conclusion, treatment with Maca improved sexual desire." 

TONGKAT ALI ROOT POWDER

TONGKAT ALI ROOT POWDER contains quassinoids and alkaloids that may increase libido and male fertility. A research study documented muscle mass and strength increases. A study on Pubmed.org says "treatment resulted in significant increases in total and free testosterone concentrations and muscular force in men and women" and "the study affirms the ergogenic benefit…through enhanced muscle strength." 

SAW PALMETTO BERRY POWDER

SAW PALMETTO BERRY POWDER may increase sex drive and libido, improved kidney functions, and strengthen urinary organs that can weaken with age. 

NEURO86 LOGICAL TRIAD FORMULA

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B-VITAMINS

 B-VITAMINS, which include Vitamin B-1 (thiamine HCl) and Vitamin B-2 (riboflavin), may have a direct impact on energy levels, brain functions, and cell metabolism. 

GAMMA-AMINOBUTYRIC ACID (GABA)

GAMMA-AMINOBUTYRIC ACID (GABA) can help inhibit the activity of excited neurons or nerve cells to aid behavior, cognition, and stress response And has been shown to improve mood levels and reduce the effects of stress and anxiety.

5-HTP

5-HTP may balance serotonin levels to aid in weight loss, mood, depression, and sleeping. A study on Pubmed.org (NIH) says "It easily crosses the blood-brain barrier and effectively increases central nervous system (CNS) synthesis of serotonin. In the CNS, serotonin levels have been implicated in the regulation of sleep, depression, anxiety, aggression, appetite, temperature, sexual behaviour, and pain sensation…5-HTP has been shown to be effective in treating a wide variety of conditions, including depression, fibromyalgia, binge eating associated with obesity, chronic headaches, and insomnia." 

ASHWAGANDHA ROOT

ASHWAGANDHA ROOT: A study on Pubmed.gov says "Ashwagandha may be effective in enhancing both immediate and general memory…as well as improving executive function, attention, and information processing speed." 

ST. JOHN'S WART

ST. JOHN'S WART may enhance metabolism and battle sleeplessness, irritability, and chronic fatigue. Scientific Studies report (35700, 2016) states that St. John’s Wart “affects multiple neurotransmitters in a non-competitive synergistic manner, and may have nootropic potential.”  The meta-analysis incorporated studies that examined the effect of St. John’s Wart versus placebo on memory indices of task performance. Thirteen independent studies (published 2000–2014) involving 20 experimental comparisons met our inclusion criteria. The results showed a large positive effect of [St. John’s Wart] on cognitive performance.” A similar study states that “The herb significantly (p<0.01) improved hippocampus-dependent spatial working memory in comparison with control and alleviated some other negative effects of stress on cognitive functions.”

DISCLAIMERS

 *These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any diseases.*  The Enneagram and related neuroscientific profile tests, personality type information and any other content provided herein or on related Aretanium websites or documents are offered AS-IS and are subject to the disclaimers and other terms set forth herein. Tests, test results, personality type information and other content herein or sent via email or other electronic communication means are offered for informational purposes only. They are not intended to be used for any healthcare diagnosis or as a substitute for obtaining medical advice and treatment from an authorized and capable physician, mental health professional, or other healthcare practitioner. Aretanium Executive Group, Inc. does not claim to be a health care provider and is not a covered entity. Any test results, information, recommendations, or supplements provided by Aretanium Executive Group, Inc. are not protected health information pursuant to HIPAA laws and any statements have not been evaluated by the Food and Drug Administration (FDA). Any supplements recommended herein are not intended to diagnose, treat, cure, or prevent any disease and are based on profiles selected by individuals. Aretanium Executive Group, Inc. cannot be held responsible for any inaccurate profile selections. You should not take any health care action or supplements based upon test results, profile information, recommendations, or any other content provided by Aretanium Executive Group, Inc. without first obtaining appropriate and independent guidance from a physician or other healthcare practitioner.