All of our supplements use only the finest ingredients, undergo rigorous quality testing, and are scientifically formulated in a GMP certified facility.
Many of the ingredients used in our supplements have been clinically tested and the reports are posted on NIH Pubmed.gov or similar sites.
In the International Review Journal, Advances in Nutrition, researchers state that: “Zinc is an essential trace element that is crucial for growth, development, and the maintenance of immune function. Its influence reaches all organs and cell types, representing an integral component of approximately 10% of the human proteome, and encompassing hundreds of key enzymes and transcription factors. Zinc deficiency is strikingly common, affecting up to a quarter of the population in developing countries, but also affecting distinct populations in the developed world as a result of lifestyle, age, and disease-mediated factors. Consequently, zinc status is a critical factor that can influence antiviral immunity, particularly as zinc-deficient populations are often most at risk of acquiring viral infections.” A study on the National Institutes of Health (NIH) PubMed.gov site titled “Efficacy of zinc against common cold viruses: an overview” says “Human rhinoviruses, by attaching to the nasal epithelium via the intracellular adhesion molecule-1 (ICAM-1) receptor, cause most colds. Ionic zinc, based on its electrical charge, also has an affinity for ICAM-1 receptor sites and may exert an antiviral effect by attaching to the ICAM-1 receptors in the rhinovirus structure and nasal epithelial cells.”
A study posted on the National Institutes of Health (NIH) PubMed.gov site says elderberry: “…displays an inhibitory effect on the propagation of human pathogenic influenza viruses.” A study published in MedicalNewsToday says: “What our study has shown is that the common elderberry has a potent direct antiviral effect against the flu virus,” says one of the study’s co-authors, Golnoosh Torabian, Ph.D. “It inhibits the early stages of an infection by blocking key viral proteins responsible for both the viral attachment and entry into the host cells.”
Resources: https://www.sciencedaily.com/releases/2019/04/190423133644.htm; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056848/; https://www.ncbi.nlm.nih.gov/pubmed/11399518; https://www.medicalnewstoday.com/articles/325055; http://pennstatehershey.adam.com/content.aspx?productid=107&pid=33&gid=002880
A study posted on the National Institutes of Health (NIH) PubMed.gov site titled “Antiviral efficacy and mechanisms of action of oregano essential oil and its primary component carvacrol against murine norovirus.” Says: “Our results demonstrate that carvacrol is effective in inactivating MNV within 1 h of exposure by acting directly on the viral capsid and subsequently the RNA.” Also, “This study provides novel findings on the antiviral properties of oregano oil and carvacrol against MNV and demonstrates the potential of carvacrol as a natural food and surface (fomite) sanitizer to control human norovirus.” Another study says: “All of the five viruses inhibited by Mexican oregano oil were enveloped. The oil evidenced antiviral activity against these viruses when the cells were pre- and post-treated.” Also, “Mexican oregano essential oil and its main component, carvacrol, were effective against RNA and DNA viruses.”
Resources: https://www.ncbi.nlm.nih.gov/pubmed/24779581; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260481/; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768712/; https://www.hindawi.com/journals/ecam/2011/690346/
A study posted on the National Institutes of Health (NIH) PubMed.gov site titled “The olive leaf extract exhibits antiviral activity…” says: “A commercial plant extract derived from olive tree leaf (Olea europaea) (LExt) and its major compound, oleuropein (Ole), inhibited the in vitro infectivity of the viral haemorrhagic septicaemia virus (VHSV), a salmonid rhabdovirus.” Another posted study says: “Studies have also shown that oleuropein exhibits a significant antiviral activity against respiratory syncytial virus and para-influenza type 3 virus.” A study posted in ResearchGate say: “Therefore, we propose that O. europaea (olive leaf) could be used as a potential source of promising natural antivirals…”
Resources: https://www.ncbi.nlm.nih.gov/pubmed/15869811; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002804/; https://www.researchgate.net/publication/7868211_The_olive_leaf_extract_exhibits_antiviralactivity_against_viral_aemorrhagicsepticaemia_rhabdovirus_VHSV
Vitamin C: A study posted on the National Institutes of Health (NIH) PubMed.gov site titled “Vitamin C Is an Essential Factor on the Anti-viral Immune Responses through the Production of Interferon-α/β at the Initial Stage of Influenza A Virus (H3N2) Infection” says: “In conclusion, vitamin C plays a critical role in vivo anti-viral immune responses against influenza virus through the increase of IFN-IL-1α/β production.” Another study stated that “Three controlled trials found that vitamin C prevented pneumonia.” And “Vitamin C levels in white blood cells are tens of times higher than in plasma, which may indicate functional roles of the vitamin in these immune system cells. Vitamin C has been shown to affect the functions of phagocytes, production of interferon, replication of viruses…”
Vitamin D: A study posted on the National Institutes of Health (NIH) PubMed.gov site titled “Vitamin D increases the antiviral activity of bronchial epithelial cells in vitro.” Says “…vitamin D increased antiviral defenses most likely via cathelicidin and innate interferon pathways.” Another study titled “Vitamin D and the anti-viral state” says “Vitamin D has long been recognized as essential to the skeletal system. Newer evidence suggests that it also plays a major role regulating the immune system, perhaps including immune responses to viral infection.” Yet another study stated: “This study demonstrates for the first time a direct antiviral effect of vitamin D in an in vitro infectious virus production system.” Vitamin D regulates the production of a protein that "selectively kills infectious agents, including bacteria and viruses," explained Dr. Michael Holick, an expert on Vitamin D research from Boston University who has published more than 500 papers and 18 books on Vitamin D.
A study posted in ScienceDirect says: “We observed that direct treatment of virus with curcumin reduced infectivity of virus in a dose- and time-dependent manner for these enveloped viruses, as well as vesicular stomatitis virus.” Also, “Previously, curcumin exhibited antiviral properties against several viruses…Derivatives of curcumin also exhibited antiviral activity against enveloped viruses. Further examination revealed that curcumin interfered with the binding of the enveloped viruses to cells in a dose-dependent manner…Together, these results expand the family of viruses sensitive to curcumin and provide a mechanism of action for curcumin's effect on these enveloped viruses.” A study posted on the National Institutes of Health (NIH) PubMed.gov site says: “Besides acting directly antiviral, recent in vivo studies showed that curcumin treatment reduces lung inflammation due to IAV infection.” Also, “…curcumin seems to not only act antiviral on several arboviruses, but might also be useful for reducing the spread of arthropod vectors.” And finally, under Conclusion: “Numerous in vitro and in vivo studies have shown that curcumin is active against different viruses.”
Studies have shown that specific chemical compounds found in garlic can be highly effective at killing microorganisms responsible for many viral infections. Due to its antiviral properties, garlic has been used to treat eye and ear infections. A study on the National Institutes of Health (NIH) PubMed.gov site titled “In vitro virucidal effects of Allium sativum (garlic) extract and compounds” says: “Garlic (Allium sativum) has been shown to have antiviral activity, but the compounds responsible have not been identified. Using direct pre-infection incubation assays, we determined the in vitro virucidal effects of fresh garlic extract, its polar fraction...”
Another study in the Journal of Virology titled “Antiviral Activity of Garlic Extract on Influenza Virus” says “Although the precise mechanism has not been defined yet, it was found that garlic extract with a good selectivity index (SI) has inhibitory effect on the virus penetration and proliferation in cell culture.”
An article in Nature Reviews Immunology titled: “Magnesium regulates antiviral immunity” describes magnesium’s ability to boost the body’s antiviral immune defenses. A study posted on the National Institutes of Health (NIH) PubMed.gov site titled “Antiviral activity of magnesium…” says: “Modulation of one or more nuclear (nucleolar) processes of the host cell may be responsible for the synergistic antiviral activity.” A Science Based Medicine article states that “Magnesium really is everywhere in the body – it’s the 4th most abundant mineral. It’s involved in hundreds of different biochemical reactions and enzyme systems, supporting processes like protein synthesis, cell growth, and energy production. It has roles in nerve function, muscle control, and blood pressure. Even blood sugar regulation depends on magnesium.”
Resources: Minton, K. Magnesium regulates antiviral immunity. Nat Rev Immunol 13, 548–549 (2013). https://doi.org/10.1038/nri3501; https://www.ncbi.nlm.nih.gov/pubmed/10474217; https://sciencebasedmedicine.org/magnesium-the-cure-to-all-disease/
A study posted on the National Institutes of Health (NIH) PubMed.gov site titled “Dietary Selenium in Adjuvant Therapy of Viral and Bacterial Infections” says: “Dietary multimicronutrient supplements containing selenium up to 200 μg/d have potential as safe, inexpensive, and widely available adjuvant therapy in viral infections.” A study published in Springer Nature says “It appears that adequate levels of selenium help to protect the host against viral infection.”
A study posted on the National Institutes of Health (NIH) PubMed.gov site titled “Experimental and Clinical Pharmacology of Andrographis paniculate…” says: “In recent years, pharmaceutical chemists have synthesized numerous andrographolide derivatives, which exhibit essential pharmacological activities such as those that are anti-inflammatory, antibacterial…and antiviral.” Also, “Extracts of this plant and andrographolide exhibit pharmacological activities such as those that are immunostimulatory, antiviral.” Another study posted on ResearchGate says: “The Andrographolide contained in ApN exhibits immunostimulatory, antiviral, and antibacterial pharmacological properties.”
Boneset: A study posted on ResearchGate titled “Antiviral activity of hydroalcoholic extract from Eupatorium perfoliatum L. Against the attachment of influenza A virus” says: “Hydroalcoholic extracts from the aerial parts of E. perfoliatum (boneset) and its main active polyphenolic constituents protect cells from IAV infection by inhibiting viral attachment to the host cells.” A study conducted by researchers at Wilkes University says: “Boneset is said to be antiviral, antibacterial, anti-parasitic.”
Resources: https://www.researchgate.net/publication/302919545_Antiviral_activity_of_hydroalcoholic_extract_from_Eupatorium_perfoliatum_L_Against_the_attachment_of_influenza_A_virus; http://klemow.wilkes.edu/Eupatorium.html
Kudzu: A study posted on the National Institutes of Health (NIH) PubMed.gov site says: “Kudzu can act synergistically or additively with the current antiretroviral…and can block viruses resistant to the fusion inhibitor Enfuvirtide. Together our results highlight Kudzu’s root extract value as a supplement to current antiretroviral therapy…”
NAC: Published results on a clinical trial using NAC stated: A Trial of antiviral treatment with adjunctive NAC has shown that NAC increases GSH levels in blood and T cells, and improves stability of CD4-possitive cells…Therefore, these clinical trial results have indicated that NAC administration has not only immune-suppressive but also immuno-stimulatory effects.” A study posted on the National Institutes of Health (NIH) PubMed.gov site titled “N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules…” says: “The antiviral and anti-inflammatory mechanisms of NAC included inhibition of activation of oxidant sensitive pathways…”
Quercetin: A study posted on the National Institutes of Health (NIH) PubMed.gov site titled: “Quercetin as an Antiviral Agent…” says: “Virus entry is the initial step of the viral replication cycle; prevention of viral entry leads to suppression of viral infectivity and is an attractive antiviral strategy.” Also, “Numerous experiments have shown that quercetin exerts antiproliferative , antioxidative , antibacterial , anticancer  and antiviral  effects.” Finally, “The data indicated that quercetin exerted an obvious inhibitory effect for both H1N1 and H3N2 virus strain infections.”
A Scientific Studies report (35700, 2016) states that St. John’s Wart “affects multiple neurotransmitters in a non-competitive synergistic manner, and may have nootropic potential.” The meta-analysis incorporated studies that examined the effect of St. John’s Wart versus placebo on memory indices of task performance. "Thirteen independent studies (published 2000–2014) involving 20 experimental comparisons met our inclusion criteria. The results showed a large positive effect of [St. John’s Wart] on cognitive performance.” A similar study states that “The herb significantly (p<0.01) improved hippocampus-dependent spatial working memory in comparison with control and alleviated some other negative effects of stress on cognitive functions.”
St. John's Wort may also aid in enhancing metabolism and internal clocks to battle sleeplessness, irritability and chronic fatigue, and in removing chronic stress hormones from the body, boosting health and cognitive function. This herb may also be beneficial for women's health, since it helps reduce sensitivity of premenstrual symptoms, improves conditions of women having premenstrual and menopausal mood swings and helps alleviate pregnancy-related hemorrhoids or other stretched out areas of the body.
St. John's Wort may regulate hormonal activity as its active ingredients have strong effects on hormone regulation. The herb may lessen hypothyroidism symptoms and may aid the thyroid gland in producing adequate amounts of hormones. St. John's Wort's soothing nature and rich concentration of antioxidant and anti-inflammatory compounds may ease joint discomfort and muscle aches, and may help reduce inflammation of the cardiovascular system, helping lower blood pressure levels and stress levels on the heart.
neuroscience nootropic supplements
Phosphatidylserine naturally functions within our bodies for the maintenance and health of the cell membranes, particularly our neuronal membranes. PS is known to provide a crucial benefit of bolstering cognitive health through maintenance of proper neurotransmitter levels as well as enhancing membrane mediated signaling of neurons. With age-associated cognitive decline becoming an increasing concern, it is important to maintain healthy levels of phosphatidylserine to reinforce proper neurological functions. Supplementation of phosphatidylserine may reduce the risk cognitive dysfunction in the elderly.
A large amount of in vitro studies utilizing primary human neurons have shown that phosphatidylserine may be vital for proper neuronal function. PS is known to be important in vesicular release of neurotransmitters from presynaptic terminals, transduction of neuron-to neuron signaling, preserving Na+/K+ balance, and regulate neuronal growth homeostasis. These essential neuronal functions eventually decline with age, and their proper maintenance is required in order to maintain proper neurological health and cognition. Several pre-clinical and clinical studies have shown that dietary supplementation of phosphatidylserine has both a neuroprotective and a neuro-enhancing effect: Aged preclinical models were fed various forms of phosphatidylserine. The researchers observed a significant improvement in three different, independent cognitive tests. Ultimately the authors of the study conclude that there was an increase in psychomotor capacity and overall cognitive improvement. A study was conducted wherein scientists took brain sections and incubated them with phosphatidylserine. The sheer act of exposing the brain to more phosphatidylserine led to an increase activity of neurons.
A 2015 study posted on Pubmed.gov (NIH) states that PS "supports human cognitive functions, including the formation of short-term memory, the consolidation of long-term memory, the ability to create new memories, the ability to retrieve memories, the ability to learn and recall information, the ability to focus attention and concentrate, the ability to reason and solve problems, language skills, and the ability to communicate. It also supports locomotor functions, especially rapid reactions and reflexes."
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The therapeutic properties of the ginkgo plant are said to include treatment for blood disorders and memory problems, enhancement of cardiovascular function and to improve eye health. Gingko contains high levels of flavonoids and terpenoids, antioxidants that may provide protection against oxidative cell damage from harmful free radicals. An Examine.com study says "There appears to be a fairly reliable increase in short term memory and free recall associated with ginkgo supplementation."
Also known as the maidenhair tree, ginkgo is one of the oldest species of tree in the world. The trees can grow more than 130 feet tall and can live for over 1,000 years. Some trees in China are said to be over 2,500 years old. The tree is considered to be a "living fossil" as it has continued to survive after major extinction events. Ginkgo biloba may offer a range of health benefits, including improving cognitive function.
According to the University of Maryland Medical Center (UMM), "Gingko is widely used in Europe for treating dementia. Doctors started to use it because they thought it improved blood flow to the brain.
The benefits may include improved thinking and memory, better social behavior, and better ability to perform everyday tasks.
Ginkgo may also help alleviate the symptoms of anxiety. A study published in the Journal of Psychiatric Research found that people with generalized anxiety disorder who took ginkgo experienced better anxiety relief than those who took a placebo.
neuroscience nootropic supplements
Bacopa monnieri has been used for centuries in Ayurveda traditional medicine and has long been thought of as a “wonder herb.” Bacopa contains contains anthraquinones, phytosterol, and terpenoids, as well as numerous biologically active compounds, such as alkaloids (brahmine and herpestine), bacopasaponins, flavonoids (glucuronyl-7-apigenin, glucuronyl-7-luteolin, luteolin-7-glucoside, and luteolin), and saponins (bacogenins, bacosides, and bacopasides). These powerful compounds are responsible for the herb’s many pharmacological and therapeutic benefits. Bacopa is commonly known as a nootropic as It has been shown to help repair neurons that have become damaged, improve brain function, improve neuron communication, and protect brain cells from harmful chemicals that are responsible for neurological diseases linked to cognition and memory. Bacopa has also shown the ability to help regulate the body's response to both acute and chronic stress and may act as a potent adaptogen.
Bacopa may increase the effects of key neurotransmitters, such as serotonin, acetylcholine, noradrenaline, and dopamine, which can help bolster a sense of calm and maintain mood equilibrium. An imbalance of these key neurotransmitters is believed to play a significant role in maintaining mental health. Bacopa may be a natural anti-depressant and mood booster that lacks the side effects of some pharmaceutical drugs.
In research, bacopa has shown significant results with respect to anxiety and depression. This research showed that Bacopa did not produce any significant motor deficit, which suggests that it is unlikely to cause sedation. In another study, participants over the age of 65 who used bacopa demonstrated a decrease in both anxiety and depression.
A 2017 study posted on Pubmed.gov (NIH) documents results that "support the beneficial mnemonic effect of Bacopa Monnieri, and suggest that this effect might be because of the increase of learning-associated synaptic machinery, resulting in the long-term potentiation enhancement and strengthening of hippocampal synapses, which plays a critical role in learning and memory formation."
neuroscience nootropic supplements
Huperzine A is an herbal substance that comes from a plant called Chinese club moss (Huperzia serrata). In traditional Chinese medicine, it has been used for centuries to reduce inflammation and sharpen memory. Huperzine A may act as a cholinesterase inhibitor, which can prevent the breakdown of acetylcholine--a brain chemical essential to learning and memory.
Huperzine A is also believed to enhance learning and memory and protect against age-related cognitive decline. It may also boost energy and increase mental alertness. Several studies posted on Pubmed.gov (NIH) point to neuroprotective, cognitive function, and memory enhancement benefits.
neuroscience nootropic supplements
N-Acetyl L-Carnitine HCI (ALCAR) is known as an anti-aging nootropic that may improve brain functions as the acetyl group passes the blood-brain barrier and may improve mood, learning, and memory. It may also shuttle fuel (in the form of fatty acids) to muscle mitochondria to boost energy production and endurance while burning fat. A study posted on Pubmed.gov (NIH) says “These results indicate that ALCAR increases synaptic neurotransmission in the brain and consequently improves learning capacity.”
neuroscience nootropic supplements
VITAMIN B-12 has been shown to keep the body’s nerve and blood cells healthy. A deficiency can cause fatigue, loss of appetite, and anemia and proper suppmentation may improve energy levels.
ASHWAGANDHA ROOT: A study on Pubmed.gov (NIH) says "Ashwagandha may be effective in enhancing both immediate and general memory in people with MCI (mild cognitive impairment), as well as improving executive function, attention, and information processing speed."
L-TYROSINE is a precursor to dopamine, which may support sleep, learning, memory, and focus. A study on Pubmed.gov (NIH) says "...cognitive studies employing neuropsychological measures found that tyrosine loading acutely counteracts decrements in working memory and information processing that are induced by demanding situational conditions."
SCHISANDRA is believed to have a positive impact on the heart, lungs, and kidneys, and may have adaptogenic properties to help the body resist the effects of anxiety and stress.
SELENIUM may play a major role in supporting metabolism and thyroid function. Antioxidants may help reduce oxidative stress by keeping free radical numbers in check while lowering the risk of mental decline and thyroid problems.
PHOSPHATIDYLCHOLINE can improve communication between nerves by increasing choline and acetylcholine levels in the brain. Studies show that introverts rely more on the acetylcholine neurotransmitter, which may improve the ability to think deeply, reflect, and focus. Studies on Pubmed.gov (NIH) say "phosphatidylcholine is a precursor of choline for acetylcholine synthesis" and "can be used as a safe and effective supplement for improving the neurological health of normal individuals and that they might also be beneficial in preventing cognitive and motor disorders later in life."
VITAMIN-E OIL is a nutrient that's important for vision, reproduction, and healthy skin, blood, and brain functions. It has antioxidant properties that may protect cells against free radicals.
CHROMIUM PICOLINATE may help lower cholesterol levels and benefit heart health. A study on Pubmed.gov (NIH) says "supplementation significantly attenuated body weight gain and visceral fat accumulation compared with the placebo group."
GAMMA LINOLENIC ACID (GLA) may activate metabolism and boost fat burning and energy. A study on Pubmed.gov (NIH) says "dietary gamma-linolenic acid oil reduces body fat content and facilitates fatty acid beta-oxidation in the liver."
CONJUGATED LINOLEIC ACID (CLA) may help with fat loss, weight loss, and lean muscle mass retention.
VITAMIN B-5 (pantothenic acid and pantothenate) is vital to a healthy lifestyle and can help convert food into energy.
INOSITOL (vitamin B8) may have various benefits such as aiding with mental health, including depression and metabolism.
L-PHENYLALANINE (LPA) can be converted to L-Tyrosine and L-dopa, norepinephrine, and epinephrine, which are vital for the body’s “fight or flight” stress response.
HORNY GOAT WEED may have positive effects on libido, emotional, and sexual brain centers and enhance several emotional brain functions. Studies show it may prevent cognitive decline and the breakdown of acetylcholine, a neurotransmitter involved in memory, focus, and learning.
MACA ROOT POWDER is a nootropic that may support learning and memory. Clinical studies show libido increase, anxiety reduction, and mood enhancement. A study on Pubmed.gov (NIH) says "In conclusion, treatment with Maca improved sexual desire."
TONGKAT ALI ROOT POWDER contains quassinoids and alkaloids that may increase libido and male fertility. A research study documented muscle mass and strength increases. A study on Pubmed.org says "treatment resulted in significant increases in total and free testosterone concentrations and muscular force in men and women" and "the study affirms the ergogenic benefit…through enhanced muscle strength."
SAW PALMETTO BERRY POWDER may increase sex drive and libido, improved kidney functions, and strengthen urinary organs that can weaken with age.
B-VITAMINS, which include Vitamin B-1 (thiamine HCl) and Vitamin B-2 (riboflavin), may have a direct impact on energy levels, brain functions, and cell metabolism.
GAMMA-AMINOBUTYRIC ACID (GABA) can help inhibit the activity of excited neurons or nerve cells to aid behavior, cognition, and stress response And has been shown to improve mood levels and reduce the effects of stress and anxiety.
5-HTP may balance serotonin levels to aid in weight loss, mood, depression, and sleeping. A study on Pubmed.org (NIH) says "It easily crosses the blood-brain barrier and effectively increases central nervous system (CNS) synthesis of serotonin. In the CNS, serotonin levels have been implicated in the regulation of sleep, depression, anxiety, aggression, appetite, temperature, sexual behaviour, and pain sensation…5-HTP has been shown to be effective in treating a wide variety of conditions, including depression, fibromyalgia, binge eating associated with obesity, chronic headaches, and insomnia."
ASHWAGANDHA ROOT: A study on Pubmed.gov says "Ashwagandha may be effective in enhancing both immediate and general memory…as well as improving executive function, attention, and information processing speed."
ST. JOHN'S WART may enhance metabolism and battle sleeplessness, irritability, and chronic fatigue. Scientific Studies report (35700, 2016) states that St. John’s Wart “affects multiple neurotransmitters in a non-competitive synergistic manner, and may have nootropic potential.” The meta-analysis incorporated studies that examined the effect of St. John’s Wart versus placebo on memory indices of task performance. Thirteen independent studies (published 2000–2014) involving 20 experimental comparisons met our inclusion criteria. The results showed a large positive effect of [St. John’s Wart] on cognitive performance.” A similar study states that “The herb significantly (p<0.01) improved hippocampus-dependent spatial working memory in comparison with control and alleviated some other negative effects of stress on cognitive functions.”
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